Tiny plastic particles found in artery-clogging plaque in the neck

Plastic particles found in artery-clogging plaque in the neck have been linked to an increased risk of stroke, mini-stroke, or temporary vision loss due to blocked blood vessels. A recent study presented at the American Heart Association’s Vascular Discovery 2025 Scientific Sessions revealed that individuals with plaque in their neck arteries had higher levels of micronanoplastics compared to those with healthy arteries.

Micronanoplastics are tiny plastic particles that are a byproduct of industrial processes or the breakdown of larger plastic items. These particles can enter the environment and accumulate in the food chain, posing a potential health risk. While microplastics are visible to the naked eye, nanoplastics are microscopic and can easily penetrate cells and tissues in living organisms.

Lead study author, Ross Clark, emphasized that micronanoplastics are not just derived from plastic utensils or packaging, but also from the food and water we consume. The study, conducted at the University of New Mexico, compared the levels of plastic particles in the carotid arteries of individuals with healthy arteries, plaque without symptoms, and plaque with symptoms related to artery blockage.

The analysis revealed that individuals with plaque but no symptoms had 16 times higher levels of micronanoplastics compared to those with healthy arteries. Furthermore, individuals who had experienced stroke or other related symptoms had 51 times higher levels of plastic particles in their arteries. This suggests a potential link between micronanoplastics and cardiovascular events.

The study also examined the effects of plastic particles on inflammation markers and gene activity in plaque-stabilizing cells. While no direct link was found between plastic levels and inflammation, differences in gene activity were observed in immune cells within the plaque.

Despite the promising findings, the study has its limitations. It cannot definitively prove that micronanoplastics cause symptoms of artery disease, and further research is needed to fully understand the biological effects of these particles. Additionally, the technique used to measure plastic in biological samples may have limitations in distinguishing between plastic particles and other compounds.

Overall, the study highlights the need for continued research on the impact of plastic pollution on human health. Understanding the potential risks associated with micronanoplastics in artery plaque could lead to new strategies for preventing cardiovascular events. Further studies are warranted to explore the immunological effects of plastic particles in clogged arteries and their implications for stroke prevention.